NOUVEAUX OLIGONUCLEOTIDES ET UTILISATION D'OLIGONUCLEOTIDES MODULANT L'EXPRESSION DE LA TYROSINASE ET DE LA TYROSINASE- RELATED-PROTEIN 1 COMME AGENTS DEPIGMENTANTS

摘要

The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.