Amino nicotinate derivatives as glucokinase (GLK) modulators

摘要

Amino nicotinate derivative compounds of formula (I) or a salt, solvate or prodrug thereof are disclosed, wherein R1, R2, R3, n and m are as described in the specification. These amino nicotinate derivatives are useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. Methods for preparing these compounds of formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase are also disclosed.