发明名称 |
METHODS UTILISING G-PROTEIN COUPLED RECEPTOR 54 |
摘要 |
An association is disclosed between the elevated levels of the G-protein coupled receptor 54 (GPR54) and certain cell proliferative diseases, such as kidney cancer. The invention further relates to screening methods to identify compounds that interact with the G-protein coupled receptor to identify agonists and antagonists for diagnosis and treatment. The invention also relates to directed targeting using agents that interact with GPR54, (e.g., anti-GPR54 antibodies or peptide agonists) which are coupled to a toxin. |
申请公布号 |
WO2004096855(A3) |
申请公布日期 |
2005.06.23 |
申请号 |
WO2004US13130 |
申请日期 |
2004.04.28 |
申请人 |
WYETH;FOLLETTIE, MAXIMILLIAN, T. |
发明人 |
FOLLETTIE, MAXIMILLIAN, T. |
分类号 |
G01N33/566;G01N33/574;G01N33/74 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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