| 发明名称 |
N-(Pyrrolo(2-3-d)pyrimidin-3-ylacyl)-Glutamins{urederivate. |
| 摘要 |
<p>N-(Acyl)glutamic acid derivatives in which the acyl group is substituted with 4-hydroxypyrrolo[2,3-d]pyrimidin-3-yl group are antineoplastic agents. A typical embodiment is N-[4-(2-{4-hydroxy-6-aminopyrrolo[2,3-d]pyrimidin-3-yl}-ethyl)benzoyl] -L-glutamic acid.</p> |
| 申请公布号 |
DE122005000012(I1) |
申请公布日期 |
2005.06.23 |
| 申请号 |
DE20051200012C |
申请日期 |
1990.12.10 |
| 申请人 |
UNIV PRINCETON |
发明人 |
TAYLOR EDWARD C;KUHNT DIETMAR G;SHIH CHUAN;GRINDEY GERALD B |
| 分类号 |
C07D487/04;A61K31/195;A61K31/505;A61K31/519;A61P35/00;A61P35/02;A61P43/00;(IPC1-7):C07D487/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
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代理人 |
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