INDOLE DERIVATIVES FOR THE TREATMENT OF BONE DISEASES

摘要

This invention relates to a method for preventing and/or treating bone diseases which comprises administering a potentiator of TGF-beta activity such as the compound of the formula [I] or pharmaceutically acceptable salts thereof to human being or animals. wherein R<1> is hydrogen, etc., R<2> is optionally substituted ar(lower)alkyl or optionally substituted heterocyclic(lower)alkyl, etc., R<3> is hydrogen, optionally substituted hydroxy, etc., R<4> is hydrogen or lower alkyl, and X is CH or N.