发明名称 METHODS AND COMPOUNDS FOR MODULATING TRIGLYCERIDE AND VLDL SECRETION
摘要 The invention provides uses of autophagocytosis inducing compounds for reducing serum levels of triglycerides and VLDL and the preparation of medicaments. The invention also provides the use of autophagocytosis inducin g compounds for treating hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, hyperlipoproteinemia, atherosclerosis, arteriosclerosi s, peripheral artery disease, coronary artery disease, congestive heart failure , myocardial ischemia, myocardial infarction, ischemic stroke, hemorrhagic stroke, or diabetes, insulin resistance, hemodialysis, glycogen storage disease type I, polycystic ovary syndrome, combination thereof. The inventio n further provides methods of identifying compounds which modulate autophagocytosis.
申请公布号 CA2561746(A1) 申请公布日期 2005.06.23
申请号 CA20042561746 申请日期 2004.12.13
申请人 THE UNIVERSITY OF MANITOBA 发明人 YAO, ZEMIN;THORNE-TJOMSLAND, GRO;JAMIESON, JAMES;MARAT, ANDREA;TRAN, KHAI
分类号 A61K38/48;A61K38/17;A61K38/45;A61K45/00;A61K49/00;A61P3/06;C12Q1/02;G01N33/92 主分类号 A61K38/48
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