INSULIN-INDUCIBLE POLYPEPTIDE

摘要

An insulin-inducible polypeptide which is a partial peptide of Bacillus subtilis natto kinase having a sequence corresponding to the 50 or more consecutive amino acids starting with the amino acid at the 20-position (from the N-terminus) toward the C-terminus in the amino acid sequence constituting the natto kinase, or an amino acid sequence derived from the above sequence by deletion or addition of a plural number of amino acids or substitution thereof by other amino acids; and an oral composition containing this polypeptide. The above polypeptide and composition exhibit a therapeutic effect on diabetes when orally administered.