METHODS AND COMPOSITIONS FOR MODULATING AMYLOID BETA

摘要

Provided herein are methods and compositions for detecting, assessing and modulating beta-amyloid peptide (Abeta) levels and/or processing of amyloid precursor protein. Methods for screening and/or identifying agents that modulate processing of APP or the levels of beta-amyloid peptides, and methods for assessing presenilin activity and for modulating lipoprotein receptor-related protein (LRP), are also provided.