发明名称 2-Cyanopyrrolidinecarboxamide compound
摘要 A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X<SUP>1 </SUP>and X<SUP>2 </SUP>each is independently lower alkylene; X<SUP>3 </SUP>is -CH<SUB>2</SUB>, -CHF or -CF<SUB>2</SUB>; R<SUP>1 </SUP>is substituent, R<SUP>2 </SUP>and R<SUP>3 </SUP>each is independently H or lower alkyl; n is 0, 1, 2, 3 or 4.]having the activity inhibiting DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.
申请公布号 US2005137224(A1) 申请公布日期 2005.06.23
申请号 US20040975524 申请日期 2004.10.29
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 SHIMA ICHIRO;KURODA AKIO;OHKAWA TAKEHIKO;KUROSAKI TOSHIO;SAWADA YUKI;WADA AIKO
分类号 A61K31/4025;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D451/04;C07D453/02;C07D471/08;C07D487/08;(IPC1-7):A61K31/46;A61K31/407;C07D43/02 主分类号 A61K31/4025
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