发明名称 |
2-Cyanopyrrolidinecarboxamide compound |
摘要 |
A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X<SUP>1 </SUP>and X<SUP>2 </SUP>each is independently lower alkylene; X<SUP>3 </SUP>is -CH<SUB>2</SUB>, -CHF or -CF<SUB>2</SUB>; R<SUP>1 </SUP>is substituent, R<SUP>2 </SUP>and R<SUP>3 </SUP>each is independently H or lower alkyl; n is 0, 1, 2, 3 or 4.]having the activity inhibiting DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.
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申请公布号 |
US2005137224(A1) |
申请公布日期 |
2005.06.23 |
申请号 |
US20040975524 |
申请日期 |
2004.10.29 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
SHIMA ICHIRO;KURODA AKIO;OHKAWA TAKEHIKO;KUROSAKI TOSHIO;SAWADA YUKI;WADA AIKO |
分类号 |
A61K31/4025;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D451/04;C07D453/02;C07D471/08;C07D487/08;(IPC1-7):A61K31/46;A61K31/407;C07D43/02 |
主分类号 |
A61K31/4025 |
代理机构 |
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地址 |
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