发明名称 |
Mutated isopropylmalate isomerase |
摘要 |
The present invention provides a polypeptide comprising an amino acid sequence in which at least one amino acid is deleted, substituted or added in an amino acid sequence of isopropylmalate isomerase derived from a microorganism belonging to coryneform bacteria, wherein a coryneform bacterium which produces the polypeptide comprising the amino acid sequence as the sole isopropylmalate isomerase exhibits a partial leucine requirement in a minimal medium; a DNA encoding the polypeptide, a recombinant DNA comprising the DNA, a microorganism transformed with the recombinant DNA, and a process for producing an L-amino acid using the microorganism.
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申请公布号 |
US2005130276(A1) |
申请公布日期 |
2005.06.16 |
申请号 |
US20040508313 |
申请日期 |
2004.09.20 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
IKEDA MASATO;HAYASHI MIKIRO;OHNISHI JUNKO;MITSUHASHI SATOSHI;MIZOGUCHI HIROSHI;NAKAGAWA SATOSHI |
分类号 |
C12N1/21;C12N9/88;C12N15/61;C12P13/04;C12P13/08;C12P13/10;C12P13/14;C12P13/22;C12P13/24;(IPC1-7):C12P13/04;C07H21/04;C12N9/90 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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