发明名称 |
Tagging and recovery of elements associated with target molecules |
摘要 |
The invention provides a method for identifying elements associated with a target molecule comprising the steps of: (a) providing a probe capable of binding by specific molecular interaction to a predetermined specifically defined region of a target molecule, the probe associated with or capable of recruiting an enzyme; (b) adding a tag capable of being activated by the enzyme such that it can attach to elements in the vicinity of the enzyme; and (c) isolating elements having the tag attached thereto, wherein the defined region occurs once, twice, or in a low number of copies in the target molecule. Preferably the tag can attach only to elements in the vicinity of the enzyme. |
申请公布号 |
US2005130161(A1) |
申请公布日期 |
2005.06.16 |
申请号 |
US20050507017 |
申请日期 |
2005.03.04 |
申请人 |
FRASER PETER;CARTER DAVID;CHAKALOVA LYUBOMIRA |
发明人 |
FRASER PETER;CARTER DAVID;CHAKALOVA LYUBOMIRA |
分类号 |
G01N33/53;C12N15/09;C12Q1/28;C12Q1/68;G01N33/15;G01N33/50;G01N33/58;G01N33/68;(IPC1-7):G06F17/60;G01N33/48;G06F19/00 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|