| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a peptide compound and a composition containing the same having angiotensin-I converting enzyme inhibitory activity considered as enabling regulating blood pressure rise, widely usable in pharmaceutical preparations, quasi-drugs, food additives, functional foods, etc. for preventing and/or treating hypertension. <P>SOLUTION: The peptide compound having angiotensin-I converting enzyme inhibitory activity is represented by one or more amino acid sequences(1) to (7) mentioned below, being obtained from a liquid produced by decomposing shark cartilage or a treated product thereof by a protease. The amino acid sequences are as follows: Tyr-Phe(1), Phe-Tyr(2), Phe-Ala(3), Leu-Val-Gly(4), Leu-Ile-Gly(5), Leu-Gly-Val(6) and Ile-Val-Gly(7). Foods, cosmetics, pharmaceutical preparations or quasi-drugs each containing at least one of such peptide compounds are also provided respectively. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
