发明名称 |
Mammalian antigen-presenting T cells and bi-specific T cells |
摘要 |
The present invention is directed to mammalian bi-specific T cells and methods for using these bi-specific T cells. More specifically, the invention relates to viral specific T cells that express chimeric anti-tumor receptors. These bi-specific T cell clones are a source of effector cells that persist in vivo in response to stimulation with viral antigen, leading to long-term function after their transfer to patients with cancer and autoimmune diseases.
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申请公布号 |
US2005129671(A1) |
申请公布日期 |
2005.06.16 |
申请号 |
US20040797609 |
申请日期 |
2004.03.11 |
申请人 |
CITY OF HOPE |
发明人 |
COOPER LAURENCE;JENSEN MICHAEL |
分类号 |
A61K39/00;A61K48/00;C12N5/0783;(IPC1-7):A61K48/00;C12N5/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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