Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof

摘要

Novel pyrimidine N-oxide compounds and salts thereof, well suited for stimulating the growth of keratin fibers (e.g., the hair or the eyelashes) and/or limiting the loss thereof and/or increasing their density, have the formula (A): in which n is an integer ranging from 2 to 12; R₁ is a linear or branched, saturated or unsaturated alkyl radical, optionally substituted with a group -OR', -NR'R'' or -COOR', R₁ having from 1 to 20 carbon atoms, or is NR'R''; R₂ is hydrogen, -NR₃R₄, -OR₃, or -SR₃, wherein R₃ and R₄, which may be identical or different, are each a linear or branched, saturated or unsaturated alkyl radical, optionally substituted with a group -OR', -NR'R'' or -COOR', R₂ having from 1 to 20 carbon atoms, with the proviso that R₃ and R₄ may form part of a saturated or unsaturated ring member of 4 to 7 atoms, optionally containing at least one hetero atom; and R' and R'', which may be identical or different, are each hydrogen or a saturated, linear or branched C₁-C₃ alkyl radical.