| 摘要 |
The invention relates to the use of compounds to ameliorate or treat an condition such as a cystic fibrosis, neutropenia or other exemplified conditions. Exemplary compounds that can be used include 3beta-hydroxy- 17beta-aminoandrost-5-ene, 3beta-hydroxy-16alpha-fluoro-17beta- aminoandrost-5-ene, 3alpha-hydroxy-16alpha-fluoro-17beta- aminoandrost-5-ene, 3beta-hydroxy-16beta-fluoro-17beta- aminoandrost-5-ene, 1alpha,3beta-dihydroxy-4alpha-fluoroandrost-5- ene-17-one, 1alpha,3beta, 17beta-trihydroxy-4alpha-fluorandrost- 5-ene, 1beta,3beta-dihydroxy-6alpha-bromoandrost-5-ene, 1alpha- fluoro-3beta,12alpha-dihydroxyandrost-5-ene-17-one, 1alpha-fluoro- 3beta,4alpha-dihydroxyandrost-5-ene and 4alpha-fluoro-3beta, 6alpha, 17beta-trihydroxyandrostante.
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