| 摘要 |
Spirofluorenols (for example, 3',9'-dimethoxy-5'- hydroxyspiro[(1H-cyclopento[d,e,f]phenanthrene)-1,7'-benzo-[c] fluorene]) are prepared by a process which comprises protecting the hydroxyl group of a specific fluorenone compound (for example, 3,9- dimethoxy -5-hydroxybenzo[c]fluoren-7-one) with a substituted silyl group wherein the substituents bonded directly to the silicon atom have 5 to 12 carbon atoms in total (for example, t-butyldimethylsilyl), reacting the protected fluorenone compound with a specific organometallic compound (for example, 1-lithiophenanthrene) to form a spiro compound, and then deblocking the spiro compound. According to this process, spirofluorenols useful as raw materials of photochromic compounds can be efficiently prepared.
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