发明名称 METHOD FOR PREPARING VALSARTAN AND INTERMEDIATE THEREOF
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a new method for preparing a new useful intermediate in preparing valsartan. <P>SOLUTION: The method for preparing valsartan or pharmaceutically permissible salts thereof is provided, wherein the method comprises a step for opening oxazolidinone rings of a compound represented by formula (II), a step for (a) removing protecting group Q when W of formula (II) is a group of formula (A) or (b) converting CN group into 5-tetrazolyl group when W is CN, and a step for, if necessary, converting the obtained valsartan into pharmaceutically permissible salts thereof. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p>
申请公布号 JP2005154442(A) 申请公布日期 2005.06.16
申请号 JP20040335711 申请日期 2004.11.19
申请人 DIPHARMA SPA 发明人 VERARDO GIANCARLO;GEATTI PAOLA;CASTALDI GRAZIANO;TONIUTTI NICOLETTA;ALLEGRINI PIETRO
分类号 C07D263/26;A61K31/41;A61P9/12;C07B61/00;C07D257/04;C07D263/18;C07D413/10;(IPC1-7):C07D257/04 主分类号 C07D263/26
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