发明名称 |
PEPTIDE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF |
摘要 |
<p>The present invention provides a peptide derivative of formula (I) or a pharmaceutically acceptable salt thereof <CHEM> wherein X is -CH(OH)- or -CO-; R<1> is hydrogen or an amino protecting group; R<2> is hydroxyl or lower alkoxy; one of R<3> and R<4> is the side chain (R group) of lysine the amino group of which may be protected with a protecting group and the other of R<3> and R<4> is the side chain (R group) of arginine the guanidino group of which may be protected with a protecting group; and R<5> and R<6> may be the same or different and are hydrogen, lower alkyl or aralkyl. The present invention further provides a production process and use thereof.</p> |
申请公布号 |
EP1445262(A4) |
申请公布日期 |
2005.06.15 |
申请号 |
EP20020780081 |
申请日期 |
2002.11.14 |
申请人 |
TAIHO PHARMACEUTICAL CO LTD |
发明人 |
YAMAMOTO KENJI;SUDA YOSHIMITSU;ASAO TETSUJI |
分类号 |
A61K38/00;A61P1/02;C07C279/36;C07K5/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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