| 发明名称 |
PSMCs AS MODIFIERS OF THE RB PATHWAY AND METHODS OF USE |
| 摘要 |
Human PSMC genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of PSMC are provided. |
| 申请公布号 |
EP1539990(A2) |
申请公布日期 |
2005.06.15 |
| 申请号 |
EP20030784939 |
申请日期 |
2003.08.06 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
TAI, ALBERT, K.;SONG, CHUNYAN;OLLMANN, MICHAEL, MARTIN;GILLETT, LUCILE, A.;ADAMKEWICZ, JOANNE, I. |
| 分类号 |
G01N33/50;A61K;A61K39/00;A61K39/395;A61K45/00;A61K48/00;A61K49/00;A61P35/00;A61P43/00;C12N;C12N5/10;C12N15/09;C12Q1/00;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/574;(IPC1-7):C12Q1/00 |
主分类号 |
G01N33/50 |
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