发明名称 |
PROCESS FOR PRODUCING L-a-METHYLCYSTEINE DERIVATIVE |
摘要 |
A process for easily producing an L- alpha -methylcysteine derivative or its salt, which is useful as a drug intermediate, from a cheap easily procurable raw material through an enzymatic D-stereoselective hydrolysis of racemic 5-halomethyl-5-methyl-hydantoin. L- alpha -methylcysteine derivative or its salt is produced by converting racemic 5-halomethyl-5-methylhydantoin to L-5-halomethyl-5-methylhydantoin through an enzymatic D-stereoselective hydrolysis, reacting the L-5-halomethyl-5-methylhydantoin with a sulfurizing agent into L-5-methyl-5-thiomethylhydantoin and hydrolyzing the L-5-methyl-5-thiomethylhydantoin.
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申请公布号 |
EP1541692(A1) |
申请公布日期 |
2005.06.15 |
申请号 |
EP20030794104 |
申请日期 |
2003.08.27 |
申请人 |
KANEKA CORPORATION |
发明人 |
OHISHI, TAKAHIRO;NANBA, HIROKAZU;SUGAWARA, MASANOBU;IZUMIDA, MASASHI;HONDA, TATSUYA;MORI, KOUHEI;YANAGISAWA, SATOHIRO;INOUE, KENJI |
分类号 |
C07C319/06;C07C319/14;C07C323/58;C07C327/34;C07D233/76;C12P17/10;C12P41/00;(IPC1-7):C12P17/14 |
主分类号 |
C07C319/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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