PHOSPHODIESTERASE INHIBITOR

摘要

<CHEM> Äwherein n represents an integer of from 1 to 4, R<1> represents substituted or unsubstituted lower alkyl, -C(=Y)R<9> or the like, R<2> represents a hydrogen atom, substituted or unsubstituted lower alkyl or the like, R<3> represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, a substituted or unsubstituted heterocyclic group or the like, and R<4> represents halogen or the like.Ü <??>A phosphodiesterase 10A inhibitor which comprises a quinoline derivative represented by the above formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient is provided.