发明名称 |
TRANSFORMANT PRODUCING SECONDARY METABOLITE MODIFIED WITH FUNCTIONAL GROUP AND NOVEL BIOSYNTHESIS GENES |
摘要 |
An objective of the present invention is to provide a transformant altered so as to produce a secondary metabolite in which a benzene ring of the secondary product is modified at the para-position with a functional group containing a nitrogen atom. A transformant according to the present invention is a transformant of an organism producing a secondary metabolite having a benzene ring skeleton without substitution at the para-position with a functional group containing a nitrogen atom, said transformant being transformed by introducing a gene involved in a biosynthetic pathway from chorismic acid to p-aminophenylpyruvic acid so as to produce a secondary metabolite having a benzene ring skeleton substituted at the para-position with a functional group containing a nitrogen atom. Another objective of the present invention is to provide a novel gene involved in the biosynthetic pathway from chorismic acid to p-aminophenylpyruvic acid. A novel gene according to the present invention comprises genes encoding the amino acid sequences of SEQ ID NOs: 2, 4 and 6 or modified sequences thereof. <IMAGE> |
申请公布号 |
EP1223215(A4) |
申请公布日期 |
2005.06.15 |
申请号 |
EP20000962989 |
申请日期 |
2000.09.29 |
申请人 |
MEIJI SEIKA KAISHA, LTD. |
发明人 |
YANAI, KOJI;OKAKURA, KAORU;YASUDA, SHOHEI;WATANABE, MANABU;MIYAMOTO, KOICHI;MIDOH, NAOKI;MURAKAMI, TAKESHI |
分类号 |
C12N9/02;C12N9/88;C12N9/90;C12N15/52;C12P13/00 |
主分类号 |
C12N9/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|