Hybrid microfluidic chip and method of manufacture

摘要

Microfluidic system comprises a circuit board with electrodes and a lacquer coating which is structure using photolithography or electron beams to leave the electrodes free. Microfluidic system comprises a circuit board with electrodes and a lacquer coating which is structure using photolithography or electron beams to leave the electrodes free. The lacquer consists of acrylic, epoxy, phenolic or silicone resins or fluoropolymer. A second layer is applied over this which has microchannels in its outer surface. This layer is made from SYLGARD (RTM; Dow Corning, polydimethylsiloxane), other organosiloxanes, their polymerization products, silicones, polyacrylates, e.g. polymethyl methacrylate, and/or elastomers with O- or N-containing functional groups, e.g. polysulfones, -imides, -carbonates and/or -acrylonitriles. The channels are in contact with the lacquer layer and bonded to it. The electrodes are positioned in the channels. An independent claim is also included for a method for making the microfluidic system by: (a) applying a layer of lacquer made from one of the polymers described above to a circuit board with electrodes on its surface; (b) structuring the lacquer layer using photolithography or electron beams to leave the electrodes free; (c) applying a layer to this which has microchannels in its outer surface; and (d) bonding it to the lacquer layer so that the electrodes are positioned in the channels.