| 发明名称 |
Lactone integrin antagonists |
| 摘要 |
The present invention relates to a class of compounds represented by the Formula I: or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alpha<SUB>V</SUB>beta<SUB>3 </SUB>and/or the alpha<SUB>V</SUB>beta<SUB>5 </SUB>integrin.
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| 申请公布号 |
US6906051(B2) |
申请公布日期 |
2005.06.14 |
| 申请号 |
US20030717238 |
申请日期 |
2003.11.19 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
RUMINISKI PETER;PENNING THOMAS D.;JIANG LAN;DEVADAS BALEKUDRU;ROGERS THOMAS;VANCAMP JENNIFER;YUAN CHESTER |
| 分类号 |
C07D307/33;A61K31/365;A61K31/506;A61P1/02;A61P3/14;A61P9/00;A61P9/10;A61P19/02;A61P19/10;A61P21/00;A61P27/02;A61P31/12;A61P35/00;A61P35/04;A61P43/00;C07D309/30;C07D405/12;C07D405/14;(IPC1-7):A61K31/33;A61K31/505;C07D239/00;C07D407/00;C07D305/00 |
主分类号 |
C07D307/33 |
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