发明名称 SUBSTITUTED (ARYLALKYLAMINOBENZYL)AMINO-PROPIONAMIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
摘要 The invention provides new compounds of formula (I) wherein o is an integer of 1 to 4; each of R and R1, which may be the same or different, is hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy; R2 is hydrogen or C1-C4 alkyl; and a pharmaceutically acceptable salt thereof; and wherein when, at the same time, R is hydrogen, R1 is hydrogen or halogen and n is one, then R2 is other than hydrogen or methyl; and of formula (IA) wherein R3 is halogen, and a pharmaceutically acceptable salt thereof, which are active on the central nervous system (CNS) and can be used in therapy as anti-epileptics, anti-Parkinson, neuroprotective, antidepressant, anti-spastic anal hypnotic agents.
申请公布号 CA2136008(C) 申请公布日期 2005.06.14
申请号 CA19942136008 申请日期 1994.03.15
申请人 FARMITALIA CARLO ERBA S.R.L. 发明人 VARASI, MARIO;DOSTERT, PHILIPPE;PEVARELLO, PAOLO;BONSIGNORI, ALBERTO
分类号 A61K31/165;A61P25/00;A61P25/08;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07C231/10;C07C237/06;(IPC1-7):C07C237/06 主分类号 A61K31/165
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