| 摘要 |
FIELD: immunology, biotechnology, medicine. ^ SUBSTANCE: invention relates to antiidiotypical monoclonal antibody or fragment thereof for BSW17 antibody effecting on LgE Cepsilon3-region bonding to high affinity LgE receptor. Amino acid sequence is as described in specification. antiidiotypical antibody is useful as pharmaceutical composition ingredient for LgE-mediated disease treatment. Invention make in possible to prevent allergic disorders and inflammations due to inhibiting interaction between LgE Cepsilon3-region with high affinity receptor by claimed antibody. ^ EFFECT: new agent for allergic and inflammation disorder treatment. ^ 7 cl, 32 dwg, 5 tbl, 10 ex |
