СПОСОБ ОПРЕДЕЛЕНИЯ ИНДИВИДУАЛЬНОЙ ЧУВСТВИТЕЛЬНОСТИ К АНТАГОНИСТАМ КАЛЬЦИЯ И ИНГИБИТОРАМ АНГИОТЕНЗИНПРЕВРАЩАЮЩЕГО ФЕРМЕНТА ПРИ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИ

摘要

FIELD: medicine, biochemical pharmacology, cardiology. ^ SUBSTANCE: method involves determination of serum blood lipid hydroperoxides level and vascular tonus coefficient (VTC) is calculated. Favorable prognosis for effective using preparations related to angiotensin-converting inhibitors is determined at the VTC value <1.0 and indices of lipid hydroperoxides <4.5 U/l. At VTC value >=1.0 and the concentration of lipid hydroperoxides >=4.5 U/l prognosis for using preparations of angiotensin-converting enzyme inhibitor is considered to be unfavorable and prescription of preparations of calcium antagonists group is expediently. Invention proposes a new method for assay of diagnostic criteria for prescription of angiotensin-converting enzyme inhibitors and calcium antagonists. ^ EFFECT: improved assay method. ^ 2 ex