PLATINUM(II) COMPLEXES, PREPARATION AND USE

摘要

This invention relates to a method for the preparation of platinum(II) complexes, in particular dicarboxylatoplatinum(II) complexes containing a neutral bidentate ligand, such as oxaliplatin. The method includes the step of reacting a bis-dicarboxylatoplatinate(II) species with a suitable neutral bidentate ligand to form a neutral dicarboxylatoplatinum(II) complex and, if necessary, recrystallising the product to form a pure dicarboxylatoplatinum(II) complex containing a neutral bidentate ligand. The invention also relates to a method for producing a bis-dicarboxylatoplatinate(II) species, and to new platinum(II) complexes that can be made by the method of the invention.