发明名称 |
METHODS FOR OBTAINING MOLECULES WITH REDUCED IMMUNOGENICITY |
摘要 |
The invention provides a method for reducing immunogenicity of a peptide, protein or protein complex in an individual comprising introducing at least one cross-link between two amino acids in the peptide, protein or protein complex that is stable or irreversible in vivo, wherein the at least one cross-link reduces the immunogenicity of the peptide, protein or protein complex in the individual compared to an identical peptide, protein or protein complex not so cross-linked. |
申请公布号 |
WO2005051975(A2) |
申请公布日期 |
2005.06.09 |
申请号 |
WO2004US21859 |
申请日期 |
2004.07.06 |
申请人 |
AVATAR BIOTECHNOLOGIES, INC.;MARSHALL, CHRISTOPHER, P. |
发明人 |
MARSHALL, CHRISTOPHER, P. |
分类号 |
A61K38/00;C07K1/107;C07K14/55 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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