CONVERSION OF AROMATIC NITRILES INTO TETRAZOLES

摘要

The present invention relates to the conversion of aromatic nitriles to tetrazoles, comprising treatment of the cyano compound with trialkyltin chloride and sodium azide optionally in the presence of a phase transfer catalyst. The process is particularly useful in the perparation of Irbesartan,Candesartan, Losartan and Valsartan.