发明名称 |
PIPERIDINE COMPOUND AND METHOD FOR PRODUCING SAME |
摘要 |
Disclosed are a novel piperidine compound represented by the general formula [I] below which has an excellent tachykinin receptor antagonizing activity a nd pharmacologically acceptable salts thereof. [I] In the formula, ring A represents an optionally substituted benzene ring; ring B represents an optionally substituted benzene ring; R1 represents an optionally substituted hydroxyl group, a thiol group having a substituent, a sulfonyl group having a substituent, or a group represented by the following formula [II]: wherein R 11 represents a carbonyl group having a substituent or a sulfonyl group having a substituent and R12 represents a hydrogen atom or an optionally substituted alkyl group; R2 represents a hydrogen atom or the like; Z represents an oxyg en atom or a group represented by -N(R3)- wherein R3 represents an optionally substituted alkyl group or the like; R4a represents an optionally substitute d alkyl group; and R4b represents an optionally substituted alkyl group.</SDOA B>
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申请公布号 |
CA2547467(A1) |
申请公布日期 |
2005.06.09 |
申请号 |
CA20042547467 |
申请日期 |
2004.11.26 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
KONO, RIKAKO;TAKAHASHI, MASAMI;ASAI, HIDETOSHI;YAMANAKA, TAKESHI;MIYAKE, TSUTOMU |
分类号 |
C07D211/46;A61K31/451;A61P1/04;A61P7/02;A61P9/10;A61P9/12;A61P17/04;A61P17/06;A61P19/10;A61P25/00;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/36;A61P27/02;A61P27/16;A61P29/00;A61P37/02;A61P37/08;A61P43/00;C07D211/38;C07D211/54;C07D211/56;C07D211/58 |
主分类号 |
C07D211/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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