LOOP DILUTION SYSTEM

摘要

A loop dilution system (Figure 2a) includes a dual-loop multi-way valve (200). In a first configuration of the multi-way valve, a first loop (210) may be filled with a first solution and a second loop (205) may be filled with a second solution. In a second configuration of the multi-way valve, the first and second loops are serially connected with a pump so that their contents may be mixed with a diluent. In another aspect of the invention, an in-process mass spectrometry (IPMS) system is disclosed that uses an internal standard to determine the concentration of an analyte in a sample. The internal standard has a different molecular composition than the analyte but is sufficiently similar chemically and physically to the analyte such that it behaves substantially the same as the analyte during an ionization process in the mass spectrometer