A TRANSPLANTABLE PARTICULATE BONE COMPOSITION AND METHODS FOR MAKING AND USING SAME
摘要
A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed. The bone is not subjected to chemical extraction or decalcification. This allows for the retention of all physiologically active components of native bone. The invention hinges on the newly discovered ability of bone particles of defined sizes to exert osteoinduction by a pathway superior to and distinct from demineralized bone matrix and similar preparations.
申请公布号
WO2005032612(A3)
申请公布日期
2005.06.09
申请号
WO2004US32183
申请日期
2004.10.01
申请人
LOSTEC, INC.;MALININ, THEODORE, I.;TEMPLE, H. THOMAS;FLORES, ALVARO;BUCK, BILLY E.
发明人
MALININ, THEODORE, I.;TEMPLE, H. THOMAS;FLORES, ALVARO;BUCK, BILLY E.