发明名称 |
Process for the synthesis of pergolide |
摘要 |
A process for the synthesis of pergolide (Formula (1)) (D-6-n-propyl-8betamethylmercaptomethylergo line) from acid 9,10-dihydrolysergic is herein disclosed. The process can be carried out without isolating most intermediates and is particularly convenient both from the yield and safety standpoint. Moreover, pergolide thereby obtained is highly pure and can be conveniently transformed into pergolide mesylate.
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申请公布号 |
US2005124812(A1) |
申请公布日期 |
2005.06.09 |
申请号 |
US20040507620 |
申请日期 |
2004.09.14 |
申请人 |
CABRI WALTER;PAISSONI PAOLO;ROLETTO JACOPO;FONTE PIERA;OLMO SARA |
发明人 |
CABRI WALTER;PAISSONI PAOLO;ROLETTO JACOPO;FONTE PIERA;OLMO SARA |
分类号 |
C07D471/04;C07D457/02;C07D457/04;(IPC1-7):C07D457/02 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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