发明名称 |
NOVEL COMPOSITIONS AND METHODS FOR THE IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF OVARIAN CANCER |
摘要 |
The present invention is directed to the identification of markers that can be used to determine whether ovarian cancer is sensitive or resistant to a therapeutic agent. In particular, the present invention is directed to the use of certain combinations of markers, wherein the expression of the markers correlates with sensitivity or resistance to a therapeutic agent. Thus, by examining the expression of the individual markers of a marker set, also referred to as the expression profile of the marker set, it is possible to determine whether a therapeutic agent, or combination of agents, will be most likely to reduce the growth rate of the ovarian cancer. |
申请公布号 |
WO03072023(A3) |
申请公布日期 |
2005.06.09 |
申请号 |
WO2003US03941 |
申请日期 |
2003.02.10 |
申请人 |
MILLENIUM PHARMACEUTICALS, INC. |
发明人 |
DAMOKOSH, ANDREW, I;IARTCHOUK, NATALIA;STEC, JAMES, J., II;CLARK, EDWIN, A.;LU, KAREN;HARTMANN, LYNN |
分类号 |
A61K31/337;A61K33/24;C12Q1/68;G01N33/50;G01N33/574;(IPC1-7):C12Q1/68;G01N33/53 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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