DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH POTASSIUM CHANNEL, SUBFAMILY K, MEMBER 6 (KCNK6)

摘要

The invention provides a human KCNK6 which is associated with the cardiovascular diseases, cancer, dermatological diseases, endocrinological diseases, metabolic diseases, gastroenterological diseases, hematological diseases, neurological diseases, urological diseases and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, cancer, dermatological diseases, endocrinological diseases, metabolic diseases, gastroenterological diseases, hematological diseases, neurological diseases, urological diseases and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of KCNK6 as well as pharmaceutical compositions comprising such compounds.