<p>It is intended to provide a method of inhibiting the multimerization of procaspase (1) characterized by comprising inhibiting the binding of NOD2 to procaspase (1) and an inhibitor therefor; a method of inhibiting the activation of procaspase 1 and an inhibitor therefor; a method of inhibiting the formation of procaspase (1) and an inhibitor therefor; a prevention method and/or a treating method for inflammatory diseases; a preventive and/or a remedy for inflammatory diseases; a method of identifying a compound inhibiting the binding of NOD2 to procaspase (1); and a reagent kit to be used in the identification method.</p>
