发明名称 |
QUINAZOLINONE COMPOUNDS WITH REDUCED BIOACCUMULATION |
摘要 |
A variety of small molecule, guanidine-containing molecules capable of actin g as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the formula IA and IB. IA and IB have the following structures where Z has the formula shown below and the rest of the variables are defined herein.</SDOAB >
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申请公布号 |
CA2545601(A1) |
申请公布日期 |
2005.06.09 |
申请号 |
CA20042545601 |
申请日期 |
2004.11.19 |
申请人 |
SPEAKE, JASON, D.;BOYCE, RUSTUM S.;CHIRON CORPORATION;GLAXOSMITHKLINE |
发明人 |
SPEAKE, JASON D.;BOYCE, RUSTUM S.;PHILLIPS, JAMES |
分类号 |
A61K31/497;A01N43/54;A61K31/517;C07D217/24;C07D239/80;C07D239/82;C07D239/91;C07D239/95;C07D239/96;C07D253/08;C07D401/00;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/00;C07D403/04;C07D403/06;C07D403/12;C07D403/14;C07D405/12;C07D413/00;C07D417/00;C07D417/04;C07D417/14;C07D419/00;C07D471/04;C07D487/04 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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