NEW FUSED IMIDAZOLE DERIVATIVE

摘要

PROBLEM TO BE SOLVED: To provide a compound having a DPPIV (dipeptidyl peptidase IV) inhibitory activity useful as a treating/preventing/improving agent of diseases of diabetes mellitus, etc. SOLUTION: This fused imidazole compound is expressed by general formula (wherein, T1is a single ring-formed or two ring-formed 4 to 12-membered heterocyclic ring which may have substituents, and containing one or two nitrogen atoms in the ring; X is a 1-6C alkyl which may have substituents; Z1, Z2are each independently N or a group expressed by formula: CR2; and R1, R2are each independently H, a 1-6C alkyl which may have substituents or a 1-6C alkoxy which may have substituents) or its salts or its hydride. These new compounds exhibit excellent DPPIV inhibitory activities. COPYRIGHT: (C)2005,JPO&NCIPI