发明名称 SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R)
摘要 <p>The invention relates to compounds of the general formula (I). (I) wherein R&lt;1&gt;, R&lt;2&gt;, R&lt;3&gt;, R&lt;4&gt;, R&lt;5&gt;, R&lt;6&gt;, R&lt;7&gt;, R&lt;8&gt;, and X are as defined in the description, or pharmaceutically acceptable salts, hydrates, geometrical isomers, racemates, tautomers, optical isomers, N-oxides and prodrug forms thereof. The compounds may be used for the treatment or prophylaxis of disorders related to the MCH1R receptor and for modulation of appetite. The invention also relates to such use as well as to pharmaceutical formulations comprising a compound of formula (I).</p>
申请公布号 WO2005051380(A1) 申请公布日期 2005.06.09
申请号 WO2004SE01619 申请日期 2004.11.09
申请人 BIOVITRUM AB;SCOBIE, MARTIN;BROWNING, ANDREW 发明人 SCOBIE, MARTIN;BROWNING, ANDREW
分类号 C07D209/12;C07D401/06;C07D403/06;C07D405/04;C07D409/06;C07D409/12;(IPC1-7):A61K31/40;A61P3/04;C07D209/32;C07D209/08;A61K31/404 主分类号 C07D209/12
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