发明名称 |
ADJUVANTS OF IMMUNE RESPONSE |
摘要 |
The present invention features methods to substantially increase the immunogenicity of a vaccine, preferably a DNA vaccine, and involves providing a mammal with a vaccine regimen, which includes an immunogen and Flt3L in combination with MIP-lalpha or MIP-3alpha. The methods of the present invention can be used for the prevention and treatment of various pathological states, including for example, cancer, microbial infections, autoimmune diseases, tissue rejection, and allergic reactions. |
申请公布号 |
WO2005052119(A2) |
申请公布日期 |
2005.06.09 |
申请号 |
WO2004US38865 |
申请日期 |
2004.11.19 |
申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER;BAROUCH, DAN, H.;SUMIDA, SHAWN, M.;LETVIN, NORMAN, L. |
发明人 |
BAROUCH, DAN, H.;SUMIDA, SHAWN, M.;LETVIN, NORMAN, L. |
分类号 |
A61K39/00;A61K39/39;A61K45/00;A61K45/06;C12N |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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