发明名称 |
ANTIBODIES TO TREAT CANCER |
摘要 |
Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell. |
申请公布号 |
WO2004053102(A3) |
申请公布日期 |
2005.06.09 |
申请号 |
WO2003US39771 |
申请日期 |
2003.12.11 |
申请人 |
UNIVERSITY OF MASSACHUSETTS;CORIXA CORP;FANGER, GARY;FANGER, NEIL;KING, DAVID;RETTER, MARC, W.;ROCK, KENNETH, L. |
发明人 |
FANGER, GARY;FANGER, NEIL;KING, DAVID;RETTER, MARC, W.;ROCK, KENNETH, L. |
分类号 |
C07K16/30 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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