SYSTEM, METHOD AND COMPUTER PRODUCT FOR PREDICTING PROTEIN-PROTEIN INTERACTIONS
摘要
System, method and computer product for predicting protein-protein interactions. In this disclosure, there is at least one biological data source containing biological data. A protein-protein interactions prediction module accesses the at least one biological data source and predicts interactions with a target protein having known domain and motif information. The prediction module includes a search module that searches the at least one biological data source for a set of proteins with domain and motif information similar to the domain and motif information of the target protein. An extraction module extracts interaction proteins from the set of proteins. A cellular location module determines whether the extracted interaction proteins are co-located at the same cellular location as the target protein. An analysis module determines protein-protein interactions of the interaction proteins with the target protein based on interaction domains and motifs and cellular location.
申请公布号
WO2004104900(A3)
申请公布日期
2005.06.09
申请号
WO2004US10395
申请日期
2004.04.05
申请人
GENERAL ELECTRIC COMPANY;ZHAO, MING;TEMKIN, JOSHUA, MICHAEL