发明名称 SPECIFIC ANTIBODIES TO AMYLOID BETA PEPTIDE, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
摘要 The invention relates to methods of treating a subject having Alzheimer's Disease, comprising the step of administering an antibody molecule which is targeted to &bgr; amyloid peptide or to fragment thereof. In another embodiment the invention relates to methods of treating a disease or a disorder, characterized by amyloid beta deposition. In another embodiment, the invention relates to an antibody molecule, which is free end-specific for the N-terminus or the C-terminus of an amyloid &bgr; peptide and to a pharmaceutical composition thereof. In another embodiment, the invention relates to an antibody molecule, which is targeted to the free C or N-terminus of a N-and/or C-terminus truncated amyloid &bgr; peptide fragment.
申请公布号 EP1487488(A4) 申请公布日期 2005.06.08
申请号 EP20020807019 申请日期 2002.10.21
申请人 MINDSET BIOPHARMACEUTICALS USA INC. 发明人 CHAIN, DANIEL, G.
分类号 A61K39/395;A61K48/00;A61P25/28;C07K14/47;C07K16/18;C12P21/08 主分类号 A61K39/395
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