| 发明名称 |
CHIMERIC CYTOKINES AND USES THEREOF |
| 摘要 |
Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient. |
| 申请公布号 |
EP0793504(B1) |
申请公布日期 |
2005.06.08 |
| 申请号 |
EP19950943058 |
申请日期 |
1995.12.12 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. |
发明人 |
STROM, TERRY, B.;ZHENG, XIN-XIAO;STEELE, ALAN |
| 分类号 |
C12N15/09;A61K38/00;A61K38/19;A61K38/20;A61K38/21;A61K39/395;A61K47/48;A61P35/00;A61P43/00;C07K14/52;C07K14/525;C07K14/535;C07K14/54;C07K14/555;C07K14/76;C07K14/765;C07K16/18;C07K16/46;C07K19/00;C12N15/02;C12N15/62;C12P21/02 |
主分类号 |
C12N15/09 |
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