发明名称 GAMMA SECRETASE INHIBITORS.
摘要 <p>This invention discloses novel gamma secretase inhibitors of the formula:(Chemical formula should be inserted here as it appears on abstract in paper form)wherein: R1 is a substituted aryl or substituted heteroaryl group; R2 is an R1 group, alkyl, -X(CO)Y, or alkylene-X(CO)Y wherein X and Y are as defined herein; each R3 and each R3A are independently H, or alkyl; R11 is aryl, heteroaryl, alkyl, cycloalkyl, arylalkyl, arylcycloalkyl, heteroarylalkyl, heteroarylcycloalkyl, arylheterocycloalkyl, or alkoxyalkyl. Also disclosed is a method of treating Alzheimer s Disease using one or more compounds of the invention.</p>
申请公布号 MXPA04007659(A) 申请公布日期 2005.06.08
申请号 MX2004PA07659 申请日期 2003.02.05
申请人 PHARMACOPEIA DRUG DISCOVERY, INC. 发明人 HOBBS, DOUGLAS W.
分类号 C07D491/113;A61K31/445;A61K31/4535;A61K31/454;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/496;A61K31/5377;A61K31/541;A61K31/55;A61K31/551;A61P25/18;A61P25/28;A61P43/00;C07D211/96;C07D401/04;C07D401/12;C07D401/14;C07D405/14;C07D409/12;C07D413/12;C07D413/14;C07D417/14;C07D471/10;(IPC1-7):A61K31/442 主分类号 C07D491/113
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