发明名称 |
Hyaluronic acid derivative with urethane linkage |
摘要 |
A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-ÄO(C=O)NH-MÜp, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C2-16 hydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.
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申请公布号 |
EP1538166(A1) |
申请公布日期 |
2005.06.08 |
申请号 |
EP20040256686 |
申请日期 |
2004.10.29 |
申请人 |
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE |
发明人 |
CHEN, JUI-HSIANG;TSAI, BIN-HONG;CHANG, HSUEN-TSENG;CHEN, MUH-LAN;CHEN, YU-HUA;JAN, SHU-HUA;LIU, MEI-JUNG |
分类号 |
A61K47/36;A61K47/48;C08B37/08;(IPC1-7):C08B37/08 |
主分类号 |
A61K47/36 |
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