| 摘要 |
A non-radioactive assay which is amenable to high throughput (HT) screening for antagonists of PLC- activated Galphaq receptors and/or tyrosine kinase coupled receptors comprising the steps of measuring longer-lived Ins(1,4,5)P3 metabolites (IPn s), i.e., Ins(1,3,4,5)P4 and Ins(1,4)P2, as a means to report the PLC activity in cells or cell lysates. |
| 申请人 |
ECHELON BIOSCIENCES INCORPORATED;NEILSEN, PAUL, O.;ASSIS, EDSON;BRANCH, ANGIE, M.;DREES, BETH, E. |
发明人 |
NEILSEN, PAUL, O.;ASSIS, EDSON;BRANCH, ANGIE, M.;DREES, BETH, E. |
