发明名称 |
METHODS AND AGENTS FOR INHIBITING DYNAMIN-DEPENDENT ENDOCYTOSIS |
摘要 |
There are disclosed methods for inhibiting dynamin-dependent endocytosis in cells comprising treating the cells with an effective amount of a compound o f formula (I), or a dimeric tyrphostin, physiologically acceptable salt, or prodrug thereof. Compounds useful in the methods described are also provided . The inhibition of dynamin-dependent endocytosis of cells is applicable to th e treatment of epilepsy and neurological disorders and conditions.
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申请公布号 |
CA2556801(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
CA20042556801 |
申请日期 |
2004.11.22 |
申请人 |
THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED;CHILDREN'S MEDICAL RESEARCH INSTITUTE |
发明人 |
HILL, TIMOTHY ADRIAN;ROBINSON, PHILLIP J.;MCCLUSKEY, ADAM |
分类号 |
A61K31/275;A61P25/00;C07C255/34;C07C255/40;C07C255/41;C07D213/80;C07D295/185;C07D311/64;C07D407/12 |
主分类号 |
A61K31/275 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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