发明名称 |
Antibody-containing solution pharmaceuticals |
摘要 |
An antibody-containing solution formulation comprising an organic acid and a surfactant as stabilizers; a method for suppressing the formation of visible insoluble matter and/or insoluble particles due to the presence of metal ions in an antibody-containing solution formulation, which comprises adding an organic acid to the solution; a method for suppressing the formation of visible insoluble matter and/or insoluble particles during shaking and freezing-thawing of an antibody-containing solution, which comprises adding a surfactant to the solution; and a method for stabilizing an antibody-containing solution, which comprises adding an organic acid and a surfactant.
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申请公布号 |
US2005118163(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
US20040504025 |
申请日期 |
2004.08.09 |
申请人 |
MIZUSHIMA HIDEFUMI;MIYAUCHI EIICHI |
发明人 |
MIZUSHIMA HIDEFUMI;MIYAUCHI EIICHI |
分类号 |
A61K9/08;A61K9/00;A61K39/395;A61K47/04;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/34;C07K16/30;C07K16/40;C07K16/44;(IPC1-7):A61K39/395;A61K31/19 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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